High intraoperative O2 decreases SSIs and PONV | allnurses

High intraoperative O2 decreases SSIs and PONV

  1. 0
    Anesthesiology. 2013 Aug;119(2):303-16. doi: 10.1097/ALN.0b013e31829aaff4.
    Effect of intraoperative high inspired oxygen fraction on surgical site infection, postoperative nausea and vomiting, and pulmonary function: systematic review and meta-analysis of randomized controlled trials.

    Hovaguimian F, Lysakowski C, Elia N, Tramr MR.
    Source

    Division of Anesthesiology, Geneva University Hospitals, Geneva, Switzerland. frederique.hovaguimian@usz.ch

    Abstract

    BACKGROUND:

    Intraoperative high inspired oxygen fraction (FIO2) is thought to reduce the incidence of surgical site infection (SSI) and postoperative nausea and vomiting, and to promote postoperative atelectasis.
    METHODS:

    The authors searched for randomized trials (till September 2012) comparing intraoperative high with normal FIO2 in adults undergoing surgery with general anesthesia and reporting on SSI, nausea or vomiting, or pulmonary outcomes.
    RESULTS:

    The authors included 22 trials (7,001 patients) published in 26 reports. High FIO2 ranged from 80 to 100% (median, 80%); normal FIO2 ranged from 30 to 40% (median, 30%). In nine trials (5,103 patients, most received prophylactic antibiotics), the incidence of SSI decreased from 14.1% with normal FIO2 to 11.4% with high FIO2; risk ratio, 0.77 (95% CI, 0.59-1.00). After colorectal surgery, the incidence of SSI decreased from 19.3 to 15.2%; risk ratio, 0.78 (95% CI, 0.60-1.02). In 11 trials (2,293 patients), the incidence of nausea decreased from 24.8% with normal FIO2 to 19.5% with high FIO2; risk ratio, 0.79 (95% CI, 0.66-0.93). In patients receiving inhalational anesthetics without prophylactic antiemetics, high FIO2 provided a significant protective effect against both nausea and vomiting. Nine trials (3,698 patients) reported on pulmonary outcomes. The risk of atelectasis was not increased with high FIO2.
    CONCLUSIONS:

    Intraoperative high FIO2 further decreases the risk of SSI in surgical patients receiving prophylactic antibiotics, has a weak beneficial effect on nausea, and does not increase the risk of postoperative atelectasis.

    http://www.ncbi.nlm.nih.gov/pubmed/23719611


  2. Visit  wtbcrna profile page

    About wtbcrna, MSN, DNP, CRNA

    From 'US'; 43 Years Old; Joined Jul '05; Posts: 4,634; Likes: 4,690.

    1 Comments so far...

  3. Visit  puppies'n kittens profile page
    0
    Conversely, More than one study has shown intentional intraop hypercarbia to reduce SSIs.


Nursing Jobs in every specialty and state. Visit today and find your dream job.

Visit Our Sponsors
Top
close
close