Pt is a female in her 60s, presents to ecc complaining of generalized weakness, anorexia, nausea, vomiting, generalized abdominal discomfort, and weight loss x 6 months.
History of hypertension and chronic back pain. Only home medication is lorcet which pt admits to taking every hour for an unknown length of time in an attempt for pain relief.
Initial vital signs: temp 98.5F oral, HR 120s-140s atrial fibrillation, BP 150s/100s, RR 20, SPO2 98% on room air.
On exam pt appears cachexic, jaundiced, is alert and oriented to person place and time but clearly has some confusion as demonstrated by not knowing how long she was taking the extra lorcet tabs, peripheral pulses, no cardiac murmurs noted, lungs clear bilaterally, bowel sounds normoactive in all 4 quadtants, no tenderness or obvious masses on palpation of the abdomen, +2 pitting edema to bilateral lower extremities, denies trauma.
Abnormal labs: potassium 1.7 (this was rechecked on the same sample and a new sample was sent to triple check), bili 3, hemoglobin 10, creatinine 2.4, acetaminophen 5.
Normal labs: wbc, ast, alt, magnesium, calcium.
Pending labs: hepatitis panel, hiv.
Per poison control as ast and alt are normal chronic acetaminophen overdose causing jaundice is not possible
Potassium replacement is started about 1hr into pts stay: 40meq in 1L NS at 500mls/hr into each arm (1000mls/hr of this solution total), 2G magnesium sulfate given. At this point pt has 22G bil forearms and 18G R ac.
Ultrasound RUQ and CT abd/pelvis ordered but are deferred due to concerns from rn and md of pt having a lethal arrhythmia outside of the ecc.
1hr after potassium replacement is started level is rechecked and found to be 2.3 (2 hours into pts stay)
3 hrs into pts stay pt was assisted onto bedpan, immediately lost consciousness for ~15 seconds, did not lose pulse but HR decreased to the 50s during this period, remained atrial fibrillation. Pt was then able to wake up and speak to staff but was clearly "in a fog", GCS 14, vitals essentially same as arrival.
3.5 hours into pts stay: md and rn at bedside, pt is acting same as 1/2 hour ago, pt has sudden decrease in loc, GCS 5, HR 50s atrial fibrillation, BP 80s/40s, pulse present. Pt is ambu bagged while being moved to trauma room. Pt lost a pulse, PEA on monitor, BLS and ACLS measures started, humeral IO, intubated (moderate amount of blood required suctioning), and femoral triple lumen placed. Along with the usual acls meds, pt recieved 80meq iv potassium bolus, 6g iv magnesium sulfate, and 120mg succinylcholine. At one point pts rhythm was vtach to torsades and was defibrillated at 200joules with conversion to PEA. Pt was declared dead after 30 minutes and a bedside ultrasound showing no cardiac activity.
I'm having a hard time with this case because we never really found out what was wrong with this pt. Unsure why pt coded, undiagnosed pancreatic cancer, aggressive potassium replacement, hypokalemia, acetaminophen overdose, or other cause? Thoughts?
Pt is a female in her 60s, presents to ecc complaining of generalized weakness, anorexia, nausea, vomiting, generalized abdominal discomfort, and weight loss x 6 months.
History of hypertension and chronic back pain. Only home medication is lorcet which pt admits to taking every hour for an unknown length of time in an attempt for pain relief.
Initial vital signs: temp 98.5F oral, HR 120s-140s atrial fibrillation, BP 150s/100s, RR 20, SPO2 98% on room air.
On exam pt appears cachexic, jaundiced, is alert and oriented to person place and time but clearly has some confusion as demonstrated by not knowing how long she was taking the extra lorcet tabs, peripheral pulses, no cardiac murmurs noted, lungs clear bilaterally, bowel sounds normoactive in all 4 quadtants, no tenderness or obvious masses on palpation of the abdomen, +2 pitting edema to bilateral lower extremities, denies trauma.
Abnormal labs: potassium 1.7 (this was rechecked on the same sample and a new sample was sent to triple check), bili 3, hemoglobin 10, creatinine 2.4, acetaminophen 5.
Normal labs: wbc, ast, alt, magnesium, calcium.
Pending labs: hepatitis panel, hiv.
Per poison control as ast and alt are normal chronic acetaminophen overdose causing jaundice is not possible
Potassium replacement is started about 1hr into pts stay: 40meq in 1L NS at 500mls/hr into each arm (1000mls/hr of this solution total), 2G magnesium sulfate given. At this point pt has 22G bil forearms and 18G R ac.
Ultrasound RUQ and CT abd/pelvis ordered but are deferred due to concerns from rn and md of pt having a lethal arrhythmia outside of the ecc.
1hr after potassium replacement is started level is rechecked and found to be 2.3 (2 hours into pts stay)
3 hrs into pts stay pt was assisted onto bedpan, immediately lost consciousness for ~15 seconds, did not lose pulse but HR decreased to the 50s during this period, remained atrial fibrillation. Pt was then able to wake up and speak to staff but was clearly "in a fog", GCS 14, vitals essentially same as arrival.
3.5 hours into pts stay: md and rn at bedside, pt is acting same as 1/2 hour ago, pt has sudden decrease in loc, GCS 5, HR 50s atrial fibrillation, BP 80s/40s, pulse present. Pt is ambu bagged while being moved to trauma room. Pt lost a pulse, PEA on monitor, BLS and ACLS measures started, humeral IO, intubated (moderate amount of blood required suctioning), and femoral triple lumen placed. Along with the usual acls meds, pt recieved 80meq iv potassium bolus, 6g iv magnesium sulfate, and 120mg succinylcholine. At one point pts rhythm was vtach to torsades and was defibrillated at 200joules with conversion to PEA. Pt was declared dead after 30 minutes and a bedside ultrasound showing no cardiac activity.
I'm having a hard time with this case because we never really found out what was wrong with this pt. Unsure why pt coded, undiagnosed pancreatic cancer, aggressive potassium replacement, hypokalemia, acetaminophen overdose, or other cause? Thoughts?