66F

Clarification, It is within the scope of practice for CRNAs to place central lines as the OP stated assisting a CRNA. Thanks, 66F

McNamara, DR, Nafziger, AN, Menhinick, AM, Bertino JS, , Jr A dose-ranging study of gentamicin pharmacokinetics: implications for extended interval aminoglycoside therapy J Clin Pharmacol 2001 41: 374-377 You may want to review this article. High dose gent is getting alot of press lately. This article mentions doses up to 7mg/kg 66f

All I can say is to not forget what the OHC does, it gives a quick reference of CaO2 which is way more important that PO2. Your P50 will not be "normal" (i.e PO2 of 50 = CaO2 27) in compromised patients. Also the curve is a sigmoid curve which tells you that very quickly a high PO2 will minutely affect the CaO2. 90/60 is for a healthy patient, in a compromised patient it may be 90/40, etc depending on how the patient's disease process has shifted the curve and ultimately affecting CaO2. CaO2 = (1.36 x Hb x SaO2/100) + (PO2 x 0.003) So you can see that PO2 has little effect on oxygen carrying capacity (but I will say it can't hurt...............) 66F

Use the term "Dopram" in your search and you'll get hits. 66F

i'd be careful with it. here are a couple of sites with some info, it is a dirty drug with a history. if you use it and something goes wrong............. sky would be the limit for your checkbook. "caution: doxapram hydrochloride injection that contains benzyl alcohol (in canada, chlorobutanol) as a preservative must not be used in newborns and immature infants. {03} the use of benzyl alcohol in neonates has been associated with a fatal toxic syndrome consisting of metabolic acidosis and central nervous system (cns), respiratory, circulatory, and renal function impairment" http://www.drugs.com/mmx/doxapram_hydrochloride.html "a preservative-free preparation currently is not commercially available in the us. " http://www.medscape.com/druginfo/monograph?cid=med&drugid=9144&drugname=dopram+intravenous&monotype=monograph&secid=4

People don't think about this alot, but wound healing is triphasic with the first phase being an inflammatory phase that induces fever secondary to interleukin (IL-1 IL-6) proliferation. Fever means the patient will be a little tachy, that along with an average EBL for a C/S sets up the patient postoperatively for an elevated HR with lower saturations. 66F

Sounds like a lacunar infarct may have happened (occurs commonly with occlusion of particular watershed areas). 66F

Cerebral perfusion pressure (CPP) and autoregulation CPP is proportional to mean arterial pressure (MAP) if ICP > right atrial pressure (RAP), then CPP = MAP - ICP if RAP > ICP, then CPP = MAP - RAP (CVP is a measure of RAP)http://www.metrohealthanesthesia.com/edu/neuro/icTumors1.htm Also google "cerebral perfusion pressure and right atrial pressure" and you will have your answers. 66F