I've been working nights for 2 of my 4 years as a nurse and I have never grown accustomed to it. Add to that four young kids and full-time grad school, and I'm wiped. Working nights isn't just working your shift; if you have a family or other day obligations, you can't "stay on nights" and participate in real life. You spend your days off trying to recover from not enough sleep. I flip back and forth from nights to days when I'm off, and I am exhausted all of the time. I have also suffered from depression since I was a teenager, and I can feel it creeping back in. I'm in NP school now, and honestly, a big impetus to get my FCNP is so that I can work M-F 8:00-4:30 and have a normal life again. Nights suck.