Looking for problems with unknown IV compatibilities

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I am currently working on developing a project to test IV drug compatiblility and stablility. I was wondering if anyone has encountered a situation where they needed to administer a drug to a NICU patient, but there was no compatibility data, either with the solution the drug needed to be mixed with or with other drugs. I am looking for common situations that arise in the NICU, as I would like this information to be useful to as many people as possible, but I would appreciate any problems that you have come across. Thanks!

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We have this happen all the time. Our med book will often say there is no compatibility data, but our policy is to hang it anyways. This comes up with TPN all the time. The latest was with PGE, Milrinone, Fentanyl and Versed. Our policy doesn't allow us to run milrinone and PGE with the others, but as soon as we tranfer the baby to the children's hospital where they will have their surgery, they give them with the TPN mainline.

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Specializes in Neonatal ICU (Cardiothoracic).

We had a situation where even pharmacy didn't know if it was ok to flush a line containing IVIg with NS, or if it had to be D5W. Nobody knew, Neofax was inconclusive, so we flushed it with the D5W, which is what it is reconstituted in.....I'd be interested in knowing, though......I know AmphoB has to be flushed with something other than NS, usually D5w.

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I have heard conflicting info about IV Diuril.Our formulary says nada, another facility's says not compatable with TPN.:uhoh21:

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