Difference between New Grad RN program/Residency and Regular RN Staff I job?

Sometimes orientation such as learning the computer system and policies etc... in general are the same for both new grad and regular RN job .  New Grad RN programs usually provide more shadowing with a preceptor/mentor until you feel comfortable working alone.  If a new grad applies for a regular nursing job, (if hired), they may pay you a little more, but probably not expect you to need a mentor/preceptor for more than 3-4 weeks.  I know new grads that had a preceptor for as long as 6 months.  It really depends on you and your employers agreement.  

The benefit of a new grad program is basically to protect your nursing license (and patient safety/hospital liability).  There is a higher chance of a new grad loosing their nursing license if they go straight to a regular nursing job without formal training.