Zofran and SSRI'S

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Specializes in Med-Surg.

My study group were going over meds and we got to the antiemetics. Zofran is considered a serotonin receptor antagonist. Should we be looking out for drug interaction between Zofran and SSRI's?

Thanks

Liz

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Read up the nursing implications for the meds in your drug guide and see what your pharm text has to say. Are they routinely prescribed together? This is a good example of a possible pharm area question.

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I doubt it... one is a receptor antagonist, and the other blocks them from being taken up. They might not work as well together, but when I search in the online interaction lookup, I find nothing that says you couldn't take Zofran and Zoloft together. I didn't try all of them, but those two seem to be representative, so it's probably not an issue. Just an educated guess...

Good question, I'll look forward to any other answers!

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