When I write orders for a patient to be NPO, and still want them to have certain po meds, I'll write the order exactly that way. "NPO after [time] except may take AM meds with a sip of water." If there is any doubt, seek clarification to avoid a "med error". There is still customary appropriateness for the NPO after midnight dictum for adult patients having first-thing-in-the-morning surgery. Such NPOness harms almost no adults. Healthy patients who aren't terrified (terror shuts off digestion/absorption) are probably safe with NPO for 4 hours for clear liquids and 6 hours for anything else. For children, the NPO criteria slide depending upon age. I'll abide a 2 hour NPO status for a 1 y/o, for example. Regurgitation/aspiration is a SERIOUS situation and can result in long recovery periods, though fortunately, rarely results in death.