My program was fairly competitive and I received a C in Chemistry II and still got in. There are many aspects to the application including an entrance letter and extracurricular activities. I think it does depend on the program as some are more focused on grades then others. I know other people who had similar GPA's as me who were wait listed, so I think that it depends on more than one aspect. You need to base your decision on what the entrance GPA is for your particular school and what their requirements are.