Was prepped with Chloraprep for hand/wrist surgery on 4/16/12. By that evening I had a shingles-like burning/itching on the preppped area. Washed off what I could and applied Benadryl cream, to no avail. By the next evening, additionally had itchy rash on trunk and shortness of breath. Oral Benadryl relieved the new symptoms, but not the burning itch. Went to the surgeon's office where they cleaned the area (not the incision sites) with Aloe wipes. I applied more Benadryl cream. It is now 4 days, still itching, and when I uncovered the incision today because it was more tender, found it was red, swollen, and the area covered with blisters. I'm very unhappy that the manufacturer and medical journals deny adverse effects despite overwhelming online evidence to the contrary.