yes neurosurgeons asks for setting of 10 - 15 mm on the codman drain coz thats the normal pressure inside the brain. and normally CSF production in 24hours is about 450 - 500ml. u hav to maintain setting within normal, if u put setting less than 10 that means ur emptying more csf and leaving empty space that can cause brain to shrink and complications may occur and if u put settings more than 15 means there r more csf inside which is not helping the patient at all, and keeping the drain ineffective. take note we drain the excess csf only. if u noticed that ur drainage bag is empty check level if it is on 10 -15mm and also check patency. if drain is patent and still empty for about 2 or 3 days inform ur neurosurgeon right away coz thats the time the drain can be removed from the patient.