I've been a wound care nurse only for about the past 6 months or so. When I first started at a long term care facility, I noticed a lot of skin prep being used in my facility. In my experience so far, skin prep can toughen the skin and provide a barrier against friction. I found it most beneficial on residents with boggy heels. Applying skin prep a few times a day did toughen the skin and I think prevented further breakdown to the heels. I also use it on blisters but that's it. As far as peeling bed sheets from the resident's skin, if they need the skin prep for prevention then the heels should also be elevated off the surface of the bed to reduce pressure, which would eliminate the bedsheet issue. I looked for info online regarding using skin prep for this purpose but have never come across any. If you find any let me know but in my experience it is appropriate in some situations.