I want to just say thank you for being so compassionate toward those of us with FM. I've had a long road to find the right regimen to control my symptoms, which started after a traumatic foot injury in '91. I have gone through my share of dr. and nurses who think I'm a hypochondriac, which in and of itself can cause severe depression. :angryfire I thought I'd share some of what seems to work best for me. I use Benadryl at HS, 50mg gives me a good night's sleep and helps with some of the other auto-immune symptoms. I did use Zoloft for a time, but have been off of it for nearly a year, now. Darvocet is the only really effective pain med for me, and as of this time, I just use 1/2 tab prn. (less than three times a week) The biggest help I found was eliminating the stress in my life. I work third shift, in home health care and my husband is extremely helpful and supportive of me. He does anything around the house that could bring on an exacerbation and tries to keep things on an even keel. (Hard job, since we're rebuilding after a house fire without insurance.) I'd say, the biggest help is in reducing stress, because it just feeds the pain...the muscles get tense, start to hurt, tense up more, hurt more.... Again I want to thank you. By the way, the person who first diagnosed me was an Army ARNP.