Well, the decrease in sex drive won't bother you any; though it might your husband! It really was only temporary though...just a few months and everything was back to normal. I was a healthy weight when I started the pill and dropped 5-10 pounds. That too, stopped after a few months and I gained it back eventually. As another person stated here, I stopped menstrating which was and still is WONDERFUL. Also, only having to remember to get a shot every 12 weeks leaves little room for error. I am quite happy with it but some people do experience weight gain and or mood swings. Most people that I know who hated Depo, stopped getting it after the first shot, and like I said, it took about six months or two shots for the side effects that I did encounter, to go away.