june1925

Hi- I'm not sure if this is the right way to post or not, but I will try to respond to your questions and hope for the best. I've heard of the antibody issue, but hane had no problems as yet in that regard. My infusion nurse has remarked to me that none of her patients have experienced those problems yet either after I asked, but admittedly it's still early in the drug's uptake, so anything could still happen. I feel sleepy after my infusion, but that seems to be gone later in the day. It certainly hasn't been an issue that affects my quality of life. I didn't do well on Copaxone- and I tried for a year. I hated the daily shots, and felt pretty crummy generally. Aditionally, my MS worsened symptomatically in the year I was on it, although my MRI was essentially unchanged. Betaseron and Rebiff were even worse. When I took the full dose, I could barely move. It was awful. About PML. To my knowledge, PML has only developed with Tysabri patients WHEN they have used it in conjunction with another drug (the one I'm familiar with is Avonex.) To my knowledge, there has been NO PML in monotherapy. Again, it is still early in the drug's uptake, but that's what I know. FYI, I have also been on Novantrone, so I've sort of been around the block with MS meds. Novantrone helped my MS, but hurt my heart. Also, FYI, I am a very small shareholder in Elan, one of the companies that owns and markets Tysabri. I bought the stock because I believe in the drug( not the other way around,) but I thought I should mention that in the spirit of full disclosure. For me this drug has been a godsend. I'll stay on it for as long as I can and not look back. Hope this helps. June1925

I'm new to this board and haven't learned how to navigate yet. I know I'm in the wrong thread, but I can't seem to find the one I am searching. This is a response to a poster in Wyoming who was asking about Tysabri. I've been on it for about a year- since it was reintroduced to the market- and it's much better for me than betaseron, copaxone, or rebiff. I'm still struggling, but the treatment has been much less onerous for me than the others. No bad effects that I'm aware of- don't be afraid. June1925