Semester 2 is quite easy as it is mainly just medication administration and you have your first clinical placement. I would say semester 3 is the most challenging as you learn the most practical skills such as catheterization, wound care, etc. Semester 4 is based mainly on mental health which makes for interesting classes. Also in semester 4 you are only in class for 7 weeks and the last 7 weeks are just your pre-grad placement. Hope this helps!