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Discussion

beta blockers

can anyone tell me what kind of half life beta blockers have? both oral and IV!

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    Half life will vary greatly between individual drugs. Your best source for this information would be a good drug reference text.

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    Half life will vary greatly between individual drugs. Your best source for this information would be a good drug reference text.

    Ditto. Look up the drug(s) in your drug book.

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    one of our cardiologists orders metoprolol PO 12.5mg q6h (as opposed to her colleagues ordering 25mg BID)... her reasoning was that the half life was 4-6 hours and in elderly patients the dose should be reduced because of slower metabolism, therefore this regimen would keep them consistently therapeutic. whether or not this is true, i think this type of regimen might be difficult for an elderly person to remember when at home...

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    one of our cardiologists orders metoprolol PO 12.5mg q6h (as opposed to her colleagues ordering 25mg BID)... her reasoning was that the half life was 4-6 hours and in elderly patients the dose should be reduced because of slower metabolism therefore this regimen would keep them consistently therapeutic. whether or not this is true, i think this type of regimen might be difficult for an elderly person to remember when at home...[/quote']

    They can go home with daily dosing of a sustained release preparation of the drug.

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    4-5h atleast for propanolol

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