Septic Shock Question

My class is preparing for a SIM Lab dealing with Septic Shock and Multiple Organ Dysfunction. I think I'm on the right track for a question, but I'm not sure.....

The Question:

Explain why myocardial depression is almost always present in a patient with septic shock despite an initial rise in cardiac output.

My Answer:

In septic shock there is a release of vasoactive substances due to the inflammatory response. This leads to vasodilation. This vasodilation decreases systemic vascular resistance and leads to a high cardiac output because of the decrease in peripheral resistance. Despite the elevated CO, abnormalities exist in oxygen extraction in the tissues. As shock continues, compensatory mechanisms, which were previously maintaining adequate perfusion of organs, become ineffective. There will be a decrease in coronary perfusion which leads to a decrease is CO.

Am I on the right track? Thank you for your help.