After looking at this question, although #4 is certainly important, I feel I would go with #2. Hypotension and tachycardia are signs of shock, and mean that the patient is in deep trouble. Although rales and tachycardia are not a good sign, hypotension and tachycardia are worse, as they indicate that the patient's heart cannot handle the additional fluid. The patient with tachycardia and hypotension needs immediate treatment and may even need CPR and the crash cart. In contrast, rales and tachycardia are problematic, but may be just within the realm of what Lasix can handle, so long as the patient has a working kidney and is not hypotensive. That being said, full disclosure that I am only a student at this moment, and this is just my thinking based on what I know so far. My idea may change with more experience.