I am not sure how strongly they look at individual grades, I know GPA must be over 3.0 to even be considered. And I think you must pass them with a C or higher as well. I did pretty good in those courses (A) and the information that I learned from them is extremely important and helpful because the classes like Patho and Pharm really do seem to build off of them. They expect you to really know and understand the material that you have already learned in those classes to be able to do well. Hope that helps!