Hey y'all, new grad nurse here. I'm pretty cautious when it comes to running IVs. Yesterday I had an order to run vancomycin at 167 ml/hr for 90 minutes. The drug was diluted in a 250 ml bag of normal saline. I set the volume to be infused in the pump as 250 ml then it started running. This bag was not running as a piggyback, just a primary. I guess I'm confused about whether or not I used the correct VTBI. When I was in nursing school the nurses would always set the VTBI for the primary line slightly lower than the total in the bag (so say 950 for 1000 ml bag). Is it wrong that I put the VTBI as exactly what was in the bag (250 ml) yesterday? Or would the bag run dry if you do this? I guess I just wanted to make sure all the antibiotic got infused. Does the pump know when the bag is empty and air starts going through the line? I am really scared about air getting into the line! Just want to make sure I am performing the best and safest practice.