Let me jump in here. Arterial pressure is the negative "pull" on the patient's access if your delivery system is measuring pre-pump arterial pressure. So, a -250mm/hg is the max. arterial presure that should be exerted on an access. To run a patient with a more negative arterial pressure is setting the patient up for potential damage to the access and the risk of hemolysis. Venous pressure ,according to Dr. Steve Schwab, Duke University, should be no more that 60% of the QB. The easiest way to measure the venous pressure is to take a venous pressure reading with the blood pump set at 2oocc/min. Your venous pressure should be no more than 120mm/hg with a pump speed of 200. Conversely, too low vensou pressure is not good either. It is an indicator that you are not moving enough blood through your system to prevent clotting on the dialyzer. Hope this helps.