San Antonio College doesn't require an entrance exam. I would say the hardest class was chemistry. I studied pretty hard and still fell short of an A. it was an 87 to be exact Bummer. Anyways Everything else wasn't too bad. I am currently in Micro and I LOVE it. Most of the people I have spoken to said it would be the one class that brought down my GPA. As for getting into the program. I just applied to the Program for the spring so I don't know yet. I did get into Baptist though for the Fall or 2013. You have to have about 6 points to be competitive. The nursing counselor at SAC said its an A & B program. If you have more that 2 C's you don't have a great chance but its not impossible. It really depends on the group applying for that particular semester.....Hope this helps....