A few nights ago I was honored to be the Labor nurse for a friend and fellow labor nurse's daughter-in-law. The delivery was uneventful and uncomplicated and the baby perfect. I used 3 mu of pitocin to augment her contractions and following the delivery of the placenta, I bolused 30 mu of pitocin as is our standard practice. Four minutes later the patient had a 9 minute seizure and was coded. We did CPR and she was transfered to the CCU. What happened? There was no preclampsia, her spo2 and BP's were normal throughout, no hx of seizure disorder and her cat scan showed no lesions or tumors, no signs that anything was out of the ordinary. Though the doctor's are still puzzled, I have a theory that she had an allergic reaction to pitocin. After reading further, seizure is one of the side effects r/t pitocin allergy. Anyone ever had a similar experience?