johnathanr

Does anyone have anything on what happens to this antidepressant after it has passed through the liver and enzymes have reduced the drug to metabolites.I'm a bit confused about how much free drug is available for pharmacologic action at its site. I know that Citalopram binds well to plasma proteins by up to 80% but does this mean that 20% is available for action? I have until 05th Jan 2005 to figure this out. Can anyone help or perhaps direct me to an appropriate site,Cheers from a rather mild Belfast, Northern Ireland & Happy New Year, Johnathan

Hello everyone, I'm a nurse working here in Belfast, Northern Ireland. I'm currently doing a masters in CBT but have to complete a core module on pharmacotherapeutics. I'm looking at the drug Lithium and am having difficulties getting info on the original clinical trials done for this drug many years ago or if anyone knows of any present studies being done.My submission date is 05-01-05 so I don't have much time. Cheers Johnathan.