Hi thanks for the feedback . You are right I don't practice in the states although I have practised in a few different countries in the last few years . Heamodiafiltation is very common now days it combines both diffusive qualities of dialysis and the convective qualities of haemofiltration . It provides much better clearance of larger weight molecules such as B2M , it also provides better cardiovascular stability whilst being treated . The online fluid is generated from dialysate concentrates and water which goes through three ultrafilters in the machine to ensure no endotoxin contamination . The treatments are the same as dialysis in terms of time , pump speeds etc. Although the dialysate flow should be increased as the substitute fluid is diverted from there , anywhere between 9-50litres a session are used and the fluid administered pre or post dialyser . Most units have been using HDF for a few years now especially for patients who have been on dialysis for a few years and no transplant imminent . If cost is not a problem I know of units where every patient is treated using HDF .