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NurseRies's post in What is the significant sign for clotting dialyser? was marked as the answerYou're right. TMP can be high or low, indicating clotting. Venous pressure gradually increasing usually indicates either the venous chamber or dialyzer is clotting. You can always flush with 100cc to assess situation. If the filter looks clear, could be a machine issue or an access issue. Which machine do you use? The Fresenius K never had a specific alarm that indicates clotting, but TMP is the best sign.