Thank you all for your responses. A few things I want to respond to; first, that article mentioned that atypical antipsychotics work in the same way as the first generation ones, by blocking D2 dopamine receptors which could ultimately lead to greater risk for psychosis and altered brain structures. From what I've seen on NIMH's website, it seems that atypical antipsychotics aren't much more effective in treating schizophrenia, they just have a lower risk of leading to tardive dyskinesia but have MORE issues associated with metabolic problems (obesity, diabetes). That's just the impression I've gotten from several of their articles; I don't have any experience to back that up. I'm trying to learn. That being said, I am glad antipsychotics are helpful for some people! Again, I WANT this to be the case. I don't want to be "against" these medications. >>>>>"Even if the medications have some or a large part in relapse, sometimes having a time of normalcy is better then living in overwhelming chaos always...." I think that is a good thing for me to keep in mind. >>>>>"Going to work in psych nursing when you're not comfortable administering anti-psychotics makes a as much sense as going to work in an abortion clinic when you oppose abortion." Yes, I know that. That's what drove me to make the original post, and why this is a struggle; I basically wanted to hear convincing evidence about why in other people's experience, treatment with antipsychotics has been seen to be a good option for some patients. My problem is that I don't have enough real-world experience to go on, but other people here do. Another poster asked why I wanted to go into psych; I thought it was the most interesting area we studied in school, and it was the most interesting to me at clinicals. I have a lot of empathy for psych patients and would love to be there as a support person for them. Part of this has to do with my own family history and personal experience; bipolar and depression both run in my family, and I myself have major depression, and I understand to some extent what it's like to have the stigma of being "mentally ill." I'm actually on effexor for my depression, and I thank God that I was finally put on effexor (after a couple years of trying other anti-depressants that did nothing). In some ways it's a nasty medication too, but I know that for me it has been totally worth it, and I hope that other people have had the same experience with antipsychotics. I don't have an agenda in terms of this stuff, just that people get the best treatment.