I have used the chitoseal with no problems i eve used with an ACT of 240 it worked like a charm. the secret is to allow the patch to get some blood and apply firm pressure to the site and release the proximal pressure, above the insicion site, after only one minute, but do not apply too much pressure because if you hold too long with a lot of pressure when you release is like releasing a dam and you will have too much pressure into a site that is close only on the outside, if you let the blood come out while you hold pressure there is better exchange of the product with the inside of the artery and better and quiker hemostasis. good luck
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