Can you get an air embolism from a picc line? The scenario was that, a patient has a PICC line that was half way out of her/his arm, while she took a nap in the afternoon. One of the caps/ports were taken out by accident as well and was unaware of it. So one line in the PICC line had no port/cap on it and was just open to air for about 6 hours..Can a pt still develop air embolism from that? and how? please explain in detail...