There is an excellent alternative to BioPatch. The Algidex IV Patch from DeRoyal provides similar antimicrobial results. The technology uses Ionic silver based in Alginate that is impregnated onto small polyurethane discs similar to BioPatch. The antimicrobial properties of silver are well documented. NO contraindications like BioPatch. Can be used on all age populations. Best thing is that is half the cost of BioPatch.... $4.00 each.