It's not that my friend cannot use hand lotion. It's that when she's volunteering at the hospital, after she washes her hand, she's not allowed to use any type of moisturizer. I'm sure that when she gets home, she slaters on moisturizer. The Glove in a Bottle I found helps keep moisture in your hands throughout the day due to the frequent hand washing and thus the name Glove in a Bottle because it's like an invisible glove. Thank you all for your post. I have many options now.