There is also a device out there called the syvek patch, similar in size and shape to an alcohol prep. It is placed over the punture site with manual pressure held for 6-10 minutes. The patch itself is made from some type of seaweed derivative and escalates the clotting cascade by positive/negative ion charges. (It's positive the blood is Negative and it attracts blood towards it and in turn the clotting cascade is escalated.) It can be used with ACT's up to 220 and is a pretty slick little device. Low incidence of poor outcome because nothing is ever introduced into the body. The bed rest then is addressed as a 1, 2, 3... thing. 1 hour flat, up at a 45 degree angle at 2 hours, ambulate and home in 3 hours. We have been using this for about 18 months on both clean caths and interventions and we all love it. Also the newest generation of angioseal has a suture that's clipped immediately and offers less bed rest, only for 1-2 hours.