Okay, Having read everyone's posts, I would like to add my two cents, whether I am right or wrong. We hang TPN thru the central line that has lipids already in it. We are NEVER allowed to piggyback anything into it. I was surprised to read that other hospitals allow it. Secondly, we draw blood from our central lines, and have a very low incidence of infection. For a while, we had a high rate of infection, but the infection control team found that it was the type of dressings we were using, and this was changed. We keep close records on infections and the events surrounding them. We have dead-ender valves that have a blue membrane that wipes clean and is needleless. We are by policy to change them with every blood draw, but I know for a fact that I am one of the only nurses to do this. We wear gloves and clean the membrane and hub with alcohol, draw out the blood, hand it to the lab person with the alcohol wipe between our gloved hand and the hub, then draw another, and flush the line. I prefer to clamp the tubing, use the alcohol to take off the old dead-ender and attach the new one that has a syringe with my flush solution on it, then unclamp and flush. I would like to know from those that do ivpb into the tpn...do you use a separate pump or interrupt the tpn? I wonder about the drop in blood sugar as well. Also, we have a policy that allows hyperal thru a peripheral iv dependent on the osmolality of the solution. We always protest, but there are a couple of doctors that do it anyway.