Do you like the NICU itself? Do you think that once you are off orientation you may come to like the unit well enough to stick out your contract? I agree with the other poster that I would definitely line up other work before you leave this job. I would probably try to stick it out myself, but if you hate the work in addition to hating the orientation you have been given, you have to do what is best for your mental health too! Good luck. I hope a PP job comes your way soon! Hang in there and keep us posted.