I work in Scotland in anaesthesia and scrub in a busy theatre dept. I am also on-call on a 1:2 basis for organ retrieval. My experience of the whole journey thankfully is not one that involves greedy, squabbling surgeons! All cases that I have been involved in have taken place in the middle of the night, it's just the nature of the beast, theatres are available at these hours. Overall I feel quite privileged to be one of only 2 nurses at our hospital to provide care for the donors and their families. I don't so much find the experience solemn as I do respectful, I personally feel an immense amount of respect for the patient and their families, the cold hard truth of it is that unfortunately that person has died/is dying and nothing can change that, it has happened and is an inevitable part of life by the time you become involved, what I find is that by agreeing to donate their organs so that others may have a chance at life or a substantially improved one is in a way the ultimate un-selfish sacrifice and something I hold the patient in great revere for. We have 2 specialist teams fly in to actually carryout the surgery, they bring with them their own scrub nurse, my duty is to work in anaesthetics and circulating and perhaps most importantly conduct the last offices. I am always alone bar the company of the renal co-coordinator when conducting last offices, just the patient, the co-coordinator and me. I feel quite honored to be able to be so attentive and take as long as is necessary to provide the patient with the optimum level of care. From the anaesthetics point of view their is an immense amount for us to do, it's an aneathestic just like any other, no different, IV fluids, catheter, body warmers, everything as it would be in a "normal" case, we always provide opiates also, there are many anaesthetists who question the giving of analgesia to "doners" on the ground that they simply don't feel anything, but thankfully my colleagues and I both feel that it is very worthwhile and provides peace of mind of a comfortable passing. For me as others have mentioned, perhaps the most alien of all moments is when the ventilator and monitors are switched off, because it's what we are used too, because it's an integral part of what we as theatre nurses do, having no life signs, no noise is indeed a little un-nerving particularly the first time you experience it. This for me though is perhaps the only negative or somewhat distressing factor in the process. To address the initial question as to whether or not depression is a factor, for me I would have to say that it is not. Yes, dealing with children is indeed very very difficult, that's about the only time I will feel affected by the process negatively, but that is of course only human. It is immensely satisfying to receive that letter from the co-coordinator detailing the eventual recipients of the donated organs, sometimes it can be many 6 or 7 people, I find that even if I have been a little down about the case, that letter makes it all worth while and in some ways brings a smile thinking that one patient helped so many others and I was fortunate enough to be a part of that! :)