On completion of MSN or NP, one is entitled to an OPT of 12 months, I feel this is enough time to secure the right job and start the EB-2 filing assuming the right job is found and the EB-2 visa is current. I recommend that one checks eligibility for OPT and if you are entitled to it, then go for it, that gives additional 12 months to work and sufficient time to follow through on the immigration process. If eligible for OPT, the 60 days rule will not apply just yet assuming that you applied for OPT before graduation, the 60 day rule will now kick in at the end of the OPT period.