jackcrna

Short term exposure to N2O (Nirous Oxide) is generally a safe proposition in most individuals however OSHA has specific guidelines for it's safe use. While I don't know what the laws and regulations are in Canada, OSHA is very specific about the need for scavenging equipment to remove N2O from the environement during use. The maximum allowable concentration in the room air during the administration of N2O is 25 PPM. While N2O is one of the safest drugs used for sedation, analgesia, and anesthesia, it does have contraindications for it's use and it can have significant side effects with chronic exposure. It must be mixed with oxygen since 100% N2O causes hypoxemia/hypoxia. The maximum recommended concentration during anesthesia is 30%. Nitrous oxide diffuses into air containing cavities in the body. It should not be administred to individuals with bowel obstruction or free air in the cranium (possible with skull fractures or post pneumoencephalogram), pneumothorax and post tympanoplasty. Long term exposure can lead to bone marrow suppression with decreased production of WBC's. Pulse oximetry is strongly recommended as well as in line oxygen monitoring to prevent hypoxia. Contact OSHA in your state for a copy of their guidelines for the use of N2O. Additional guidelines and information can be found on the following links: http://gasbone.herston.uq.edu.au/teach/su602/docs/e27_0ent.html http://gasnet.med.yale.edu/societies/apsf/newsletter/1992/fall/index.html#art5 Jack Conscious Sedation Cliical Competencies http://www.jackstem.com/cs_competencies.htm [This message has been edited by jackcrna (edited February 11, 2001).]