Gowning and gloving would be an adequate way of protecting yourself. But one thing to remember about C. diff is it's almost entirely associated with antimicrobial use, particularly the second and third generation cephalosporins. Such ABX destroy normal flora, and in essence, create a breeding ground that is conducive to C. diff spore to vegetative cell colonization. Discontinuation of the antimicrobial agent will often resolve diarrhea symptoms in a few days. Sometimes further treatment is needed, first line Tx being Flagyl, second line Tx being Vancomycin. Recurrence ranges from 5-17%.Three events must occur to acquire CDAD (C. diff associated disease), A) Antibiotic use, B) C. diff acquisition, C) Inadequate IgG host response to toxin A of toxigenic C. diff.