I have worked as a private duty nurse (self employed) to a 8 month old infant with cardiac problems. You have to consider a few things, like others have said, you need to be in your comfort zone, should have a trusting relationship, and most of all carry your own private malpractice insurance that would cover you if there is a problem. If you do give it then make sure somewhere that you keep a note of what you gave the lot #, where, who, when and any pt teaching. This will cover you in court if need be. When my job with the infant ended, I gave a copy of my notes to the parents, the originals are in a safe deposit box for safe keeping and in keeping with the law, I will keep them for 7 years after the child turns 21. obviously if you give the shot, you would not keep it that long.