Hi started a full-time DNP program when my oldest had just turned 1. I do work PRN, probably averaged 25 hrs a week until I started clinical. I went on to have two more babies throughout the program. I took off one semester when the second was born but I didn't take any time off with my third.
I think the hours flexibility depends on the job that you get. It can be challenging to find a job, so you need to be open to many specialties.