@Evelynl - The first semester you are just getting your feet wet. The workload is HARD, and that's true for all 4 semesters. They are each challenging in their own way.
Semester 1 - Hard because you are getting used to being back in school, taking FIVE classes (that's a lot!), AND learning medical terminology and the nursing process. You are also switching your way of studying and testing from memorization to critical thinking, which is more difficult than it sounds. If you have medical *and* science background then the content isn't too difficult. If you don't have medical *and* science background, expect it all to suck. You're also placed into clinical during week 3 so you know nothing and are expected to jump right in!
Semester 2 - This was the Summer semester for us. Hard because your semester is shortened, you still have a full courseload (12 or 13 credits), and the weather is nice so you'd rather be anywhere but inside studying. Our clinicals were canceled this semester, so it was easier for us, but I could honestly not imagine the hell it would have been had we been placed in clinicals AND taking classes.
Semester 3 - The worst of all. You're taking numerous DIFFICULT classes, have three clinicals, and it all totals 17 credits. Critical care, OB, and peds are hard knowledge-wise. Then throw in all of their clinical days on top and you've got chaos. This was the semester I personally struggled with the most, and I know a lot of our classmates did too. We thought the first semester was the weed-out semester until we started third semester.
Semester 4 - Hard, but in different ways. Content? It's the BS portion of the BSN. But you're in your internship. Pray that you get a first half semester internship so you aren't struggling at the end of the semester. You will definitely have some night shifts (if not all), so you're getting used to trying to juggle 2-3 of those a week on top of your community clinicals and all of your other classes. You also have to be prepared to be placed in an internship you did not request - and appear happy and willing to learn in it. Add applying for jobs, going on interviews, and the seemingly infinite amount of projects this semester, and it's anything but a breeze.
If you are asking about first semester just because of the five classes and wondering what the workload is like, I highly encourage you to think long-term here. Nursing school is so much more than one semester. What's your home life like? Do you have a support system? Pets that need to be taken care of? A house that needs to be cleaned? Laundry that needs to be done? Kids to be taken care of? A job that you can't really quit because you need the money and/or benefits? All things to take into consideration, and all questions you need to ask yourself before truly committing to a 15 month program.