It seems that you could infuse meds that have Y site incompatibilities at the same time using a double lumen PICC, but I was wondering if there is a mixing that happens in the vein at the point where the meds leave the PICC--for example, doxorubicin through one lumen and an incompatible antibiotic through the other lumen. Is the superior vena cava big enough to dilute them immediately so no reactions between them happen?