What does platelet aggregation mean always used in regards to NSAIDS?NSAIDS should not be used during nadir period 0 Likes
ghillbert, MSN, NP Specializes in CTICU. Has 20 years experience. Feb 26, 2009 NSAIDs block COX1 or COX2, or both. COX1 leads to thromboxane formation, which causes platelet adhesion and aggregation (makes them sticky). NSAIDs block this. I don't know what the other thing you mentioned means.http://www.medscape.com/viewarticle/422939_5 0 Likes