I just finished my ADN at a school that was 60ish miles away from home. For two years I drove from home near the Oregon coast to Portland. Luckily, I found a classmate who lives nearby and we carpooled, alternating driving days. It was exhausting. Rush hour traffic made the drive almost twice as long. Two hour drive, eight hour school day, then the two hour drive home... Then there were the quarters with 12-hour clinical days.
It was worth it, though.
Driving so much definitely wears at your car. Aside from the cost of gas, I was also having to get oil changes much more frequently, went through a couple sets of tires, and had to get more than a few rock chips filled during these last couple years.