Published Jul 18, 2008
shajon22
6 Posts
:typing i have a pharmacology promblem that i been tryin to solve forever . could any help me ? hers's the word problem ;
the dose of azathioprine is 125mg/m squared/ day. find the total daily dose for a 44- pound child of average height and weight.
i used the body surface area nomogram and got .8m squared but cant get the dose i don't know where to begin help me please !!!!!!somebody any body shajon22:banghead:
Hands and Heart
217 Posts
You have the numbers there: 125 mg/m2/day. If you got 0.8 m on the nomogram, square it and you get 0.64 m2. Now for every 1 m2, you would need 125 mg. You have 0.64 as your squared meters. So 125mg/m2/day X 0.64 m2= 80 mg/day. Hope that's right. It makes sense to me.
Daytonite, BSN, RN
1 Article; 14,604 Posts
This is a case where the equation you need to use is a surface area calculation: surface area in square meters x dose. To complete the calculation you multiply the BSA by the dose (125mg). This will represent the decimal, or percentage, of the 125mg dosage that is given.
See this site: http://www.pharmacyexam.com/news/calculation.pdf
Are you sure of your BSA? I found the normal height of a 44 pound child to be 44 inches which brought the BMI to 16 and the BSA to 15.7 kg/meter squared. Didn't have a normogram to determine the percentage though.
thax a million for your help you was correct:yeah: