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Oxytocin-Life

Ob/Gyn   (6,137 Views 12 Comments)
by OBRN4U OBRN4U (New Member) New Member

OBRN4U has 12 years experience and works as a Registered Nurse, BSN.

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Does anyone know how long oxytocin (Pitocin) will last once mixed with LR. We do a concentration of 10mu in 500ml of LR and 40mu in 1,000ml of LR. Please help.

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radioactivern works as a OBGYN Triage Advice Nurse.

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I was always taught that it was good for only 24 hours once the bag was spiked and hung

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Elvish is a BSN, DNP, RN, NP and works as a OB, Nursery.

3 Followers; 17 Articles; 65,701 Visitors; 5,259 Posts

You might want to check with your hospital's pharmacy. We have premixed bags that we keep in the pyxis of 20u/1000ml D5LR. I can't remember off the top of my head how long they are good but they are stable in a closed bag at room temp for a good while, IIRC. Spiked and hung is a different story.

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casiandra works as a Certified Pharmacy Tech.

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I work in pharmacy and they are good for 24 hrs only

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8,909 Visitors; 697 Posts

Why don't you ask the pharmacist where you work?

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klone has 13 years experience as a MSN, RN and works as a Director of OB Services.

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We keep premixed (by pharmacy) bags in our Pyxis (30 in 500, which makes a 1:1 ratio which is really nice). Pharmacy doesn't mix them individually and send them to us as needed. These bags might be in our Pyxis for several days. So based on that, it's definitely more than 24 hours as another poster stated.

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babyktchr works as a Nurse Manager.

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It is one thing to live in a pyxis, they do have expirations listed on the bag. Once spiked, the bag is only good for 24 hours. Every bag of medication has an expiration date listed on it.

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klone has 13 years experience as a MSN, RN and works as a Director of OB Services.

3 Followers; 112,604 Visitors; 13,037 Posts

It is one thing to live in a pyxis, they do have expirations listed on the bag. Once spiked, the bag is only good for 24 hours. Every bag of medication has an expiration date listed on it.

I got the impression the OP was asking about after mixed, not after spiked.

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OBRN4U has 12 years experience and works as a Registered Nurse, BSN.

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Thanks for the respondes everyone. I should have been clearer about my question. I was asking how long does pitocin last once mixed and not spiked. The reason I asked, We nurses on our unit have noticed, if we hang a bag of pitocin that had been mixed greater than 24 hours for induction, the labor is long and with primigravidas, they may never reach labor. Also with postpartums, if the pitocin was mixed greater than 24 hours, they tend to bleed more. In both cases, once we change the bags to a newly mixed bag we get the results that are expected. We have talked to our pharmacy, but they state, there is no expiration date once its mixed (with the exception from the manufacturer). We even have an OB doctor that agrees with us and he too has searched for literature and was unable to find supporting information. But, we as nurses, see the difference, because we work with the product on a day to day bases. Have any of you guys noticed this as well?

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babyktchr works as a Nurse Manager.

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Interesting. I was always taught that if you mix it, it is only good for 24 hours. Even our bags or antibiotics that the pharmacy makes have expirations dates printed on the labels.

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Bree124 works as a RN.

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Our pharmacy used to mix the bags and stock 6-10 in our pyxis, with an expiration date around 72 hours after being mixed. Now we get them premixed from a manufacturer, and they don't expire for several weeks.

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17 Articles; 31,048 Visitors; 4,167 Posts

We keep our mixed (unspiked) pit bags in a med fridge. Have never noticed a difference in their effectiveness. Wonder if refrigeration prolongs the life of the oxytocin.

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