NS+Amphotericin=bad

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Can anyone tell me if mannitol is not compatible with certain fluids, like D5W or D5.9? Today I learned that amphotercin is not compatible with normal saline. No, I didn't learn the hard way. Can anyone tell me off the top of their heads any more IV meds that may not be compatible with a patient's primary, like anything that reacts with potassium, NS, D5W, etc. Please help me, I am desperate.

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Specializes in Education, FP, LNC, Forensics, ED, OB.
Can anyone tell me if mannitol is not compatible with certain fluids, like D5W or D5.9? Today I learned that amphotercin is not compatible with normal saline. No, I didn't learn the hard way. Can anyone tell me off the top of their heads any more IV meds that may not be compatible with a patient's primary, like anything that reacts with potassium, NS, D5W, etc. Please help me, I am desperate.

Mannitol is imcompatible with any blood infusion. Also, do not add KCl or NaCL to Mannitol solutions of 20% concentrations or more due to precipitation of Mannitol.

Mannitol is compatible with NS 0.9 and D5W

And there are other drugs incompatible with IV's. Look in the PDI for what each drug and/or solution are compatible with.

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Specializes in Emergency/Trauma/Education.

Some IV compatability charts (found on the inside covers of medication reference books) display this information. You might also check with a hospital pharmacy to get a more complete list.

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Specializes in Gerontological, cardiac, med-surg, peds.
Can anyone tell me if mannitol is not compatible with certain fluids, like D5W or D5.9? Today I learned that amphotercin is not compatible with normal saline. No, I didn't learn the hard way. Can anyone tell me off the top of their heads any more IV meds that may not be compatible with a patient's primary, like anything that reacts with potassium, NS, D5W, etc. Please help me, I am desperate.

If you don't know if a drug is compatible, check each time before infusing with an up-to-date drug compatibility chart, or with your hospital's pharmacist or IV additive service. There is simply no substitute for doing this. If you cannot find any reliable information, then don't take any risk - run two separate IV lines or run sequentially. Also, as a second "safety check," always take a few moments after infusion has begun to observe for precipitation.

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Specializes in ER.

we have a list of all the abx we use with the mixing solution and infusion times on a chart taped to the wall in the med room and by the omnicell.

info on other emergency drugs we give are typed up on individual pages with concentrations, solutions and drip rates and are kept in binders in a couple of different locations.

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Specializes in Pediatrics.

Cyclosporine- only compatible in D5W (as far as I know). I'll post more as I think of them...

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