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Lab vs Pharmacy-Vancomycin trough

Infusion   (2,228 Views | 2 Replies)

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According to the lab slip, it says that a normal vancomycin trough range is 5-10. The lab says that the results of 17 is a "toxic vancomycin trough". The pharmacy says "We don't know why the lab keeps saying 17 is toxic. A normal trough is 10-20" The actual lab slip specifically says that a normal vancomycin trough is 5-10. So who is correct? The lab or the pharmacy?

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IVRUS has 32 years experience as a BSN, RN and specializes in Vascular Access.

1,030 Posts; 20,875 Profile Views

Vancomycin levels have changed over the last two years. Depending on the organism that they are trying to eradicate, "normal" trough levels are anywhere from 5-20. The pharmacy should have the organism in question on file as should the lab... In previous years, a 17 trough was toxic, but not anymore.

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Asystole RN is a BSN, RN and specializes in Vascular Access, Infusion Therapy.

2,313 Posts; 27,014 Profile Views

Entirely depends upon the renal function of the patient and more importantly, the organism. ID docs will often specify a target range for the trough to suit various bugs.

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