Quick question!

  1. Does drug tolerance go away after a period of not getting the drug or not?
  2. Visit Danianne profile page

    About Danianne

    Joined: Mar '05; Posts: 163; Likes: 9
    LTCA

    3 Comments

  3. by   athena55
    Hello Danianne:
    Umm, which drug would you have in mind? Are you talking about opiates? Antihypertensives?
  4. by   Danianne
    Specifically speaking drugs like Benadryl.

    let me explain... during my clinical the nurse I was shadowing had a patient that had been on a drip of benadryl for 6 days because she had some reaction that caused her to itch, the benadryl was starting to not work.
  5. by   GeminiTwinRN
    good question, only I am curious about opiates and narcotics. for instance, if a person is on long term opiate therapy for chronic pain, and then goes off the meds, does the tolerance that has been built up then go away? will the person eventually respond to the lower doses of an opiate or narcotic that previously needed to be high due to tolerance?

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